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KMID : 1100220030020020101
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Dementia and Neurocognitive Disorders
2003 Volume.2 No. 2 p.101 ~ p.107
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Neuropathology of MCI-View from Relationships with Aging and Alzheimer’s Disease-
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Choi Kyoung-Gyu
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Abstract
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The progression of cognitive impairment toward dementia of the Alzheimer’s disease is gradual, and there is probably an intermediate or transitional stage between healthy aging and dementia of the Alzheimer type. This transitional stage has received mild cognitive imapairment (MCI). Whether MCI truly represents the prodromal or earliest clinical phase of Alzheimer’s dementia is the subject of many research. Current studies suggest that in many instances early memory are associated with specific Alzheimer related neuropathological changes in limbic areas. Many studies show evidences that there is significant neuronal loss in selected memory related structures of brains with MCI.
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KEYWORD
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MCI, Alzheimer, Aging, Neuropathology
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